#525: Multi-Cancer Early Detection Testing

Cut through the hype of Multi-Cancer Early Detection (MCED) tests and learn how to counsel patients on the real-world utility, false-positive risks, and the "stage shift" debate of these emerging blood assays. We are joined by world-renowned oncologist Dr. Margaret Tempero,UCSF Cancer Early Detection and Interception, to discuss whether these tests are truly ready for clinical prime time.

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**
Show Segments**

• 00:00 Introduction 
• 01:57 Current Cancer Screening Programs 
• 06:05 Emerging Blood-Based Cancer Tests 
• 11:55 Test Characteristics and Limitations 
• 18:05 Practical Considerations for Patients 
• 25:33 Direct-to-Consumer Testing/Whole Body MRIs
• 36:46 Navigating Positive Test Results 
• 45:10 Anxiety and Patient Education 
• 47:08 Future Directions in Cancer Screening 
• Outro

**
Credits
**

• Producer, Writer, Show Notes, Infographic, Cover Art: Molly Heublein MD
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Sai S Achi MD,MBA,FACP
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Margaret Tempero, MD

**
Disclosures**

Dr. Tempero reports the following financial relationships:
Grail (research support), Global Bio Access Fund (Advisor), Bristol Myers Squibb (Membership on Advisory Committees or Review Panels, Board Membership, etc.), Astra Zeneca (Membership on Advisory Committees or Review Panels, Board Membership, etc), Immunovia (Membership on Advisory Committees or Review Panels, Board Membership, etc.), Merck (advisory committee), Renovo Rx (advisory committee), Urogen (Advisor). Financial relationships have not ended.
The Curbsiders report no relevant financial disclosures. 

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